Need a power supply with bigger watts and quality
Hi:
Do you check that you have adequate power supply and UPS? If the power does not have enough juice, it might post with minimal attached peripherals, but not full-loaded system.
If you live at the area with a not-so-stable voltage electricity, you need a UPS as well. I had the experience that the system power-up at the morning but not other time due to the unstable voltage and was resolved after an UPS installed.
Your CPU and motherboard might be fine but the power is not quite good enough especially when you installed a new heat-sink with much power drawing fan from the motherboard.
Good luck.