In order to disable Windows Vista 64-bit OS’s digital driver signing verification, you need to restart your computer and enter the Advanced Boot Options menu by pressing F8 during the boot process. From the menu, select Disable Driver Signature Enforcement and press ENTER.
This option disables the kernel-signing enforcement only for the current boot session.
You can also permanently disable signing using bcdedit from a cmd window.
The command is bcdedit -set loadoptions DDISABLE_INTEGRITY_CHECKS
It may or may not work depending on the patches installed.