To be on the safe side I would re-install the OS. Every time I change motherboards, I format and re-install the OS. This gets rid of any unwanted drivers, and also lets you start out with a clean registry. Reading the manual for the mobo is a big help, just take your time and make sure everything is seated properly. I know it is exciting when you get to work on your computer, but really slow and easy is the safest and best way to go. Good luck and have fun installing your new mobo.