I've been using RAID 0 on my current setup for years, first with the original 120GB HD's I bought, then with the 250's I currently have, and never once had an issue. I periodically back up my data onto an external hard drive, but never once have had an issue. But yes I understand the risk involved, which is why I like OS-Wiz's idea of making a backup partition on the mechanical drives. Either way I'd only be putting Windows and programs on the SSD's, so my data would be protected on the RAID 1 setup.

As for Acronis 2010, I just looked for it online and found it getting some really horrible reviews, though they mostly seemed support related?